The vaccination is the most effective way to prevent infectious diseases. It allows us to protect ourselves and our fellow citizens. Thanks to the joint efforts of the global medical community, we are now fortunate to have access to SARS-CoV-2 vaccines. This is an essential element in the fight against COVID-19 and will help us stem the pandemic and its effects on our health and society.

Discover our 5 good reasons to get vaccinated now.

Luxembourg's COVID-19 vaccination strategy supports access to and availability of safe and effective vaccines as soon as they are made available on the market.

This will mitigate the health, social and economic consequences of the COVID 19 pandemic. The vaccine will help save lives and make the best use of our resources.

It remains important to follow hygiene rules and wear a mask during the implementation of the vaccination strategy.

COVID-19 vaccination of children between 5 and 11 years of age

Children aged between 5 and 11 years can get vaccinated on a voluntary basis.

For more information: Vaccination of children

How to get my "booster" dose - Additional vaccination shot

Immunity after vaccination against COVID-19 decreases over time. It is therefore important to strengthen your immunity with a booster dose.

You will receive an invitation from the Luxembourg Government for a booster vaccination against COVID-19.

Important: in the vaccination centres  LuxExpo, Luxembourg Air Rescue, Esch-Belval and Ettelbruck, you can only get your booster vaccination by appointment. It is therefore necessary to wait until you receive your invitation letter by post to make an appointment.

In view of the current epidemic wave, the threat of the omicron variant and the increasing incidence of hospitalisations among vaccinated persons, it has been decided to reduce the interval between the last injection of a Pfizer or Moderna vaccination and the "booster" dose.

You will receive an invitation by post, and you must respect the following deadlines to complete your booster vaccination:

  • Two-dose vaccine (Moderna, BioNTech/Pfizer) and "Mix & Match" (AstraZeneca in 1st dose and RNA in 2nd dose): 3 months after your full vaccination
  • Two-dose vaccine (both doses AstraZeneca): 3 months after your full vaccination
  • One-dose vaccine (Johnson & Johnson): extra dose by RNA vaccine 1 month after the Johnson & Johnson injection

People who have tested positive for COVID-19 can receive the booster 1 month after their positive PCR test.

The invitation will specify how to make an appointment at one of the vaccination centres or at a physician's office.

The list of physicians participating in the vaccination campaign is available here.

You can also get vaccinated in the "Pop Up Vaccination" stations: Get vaccinated - without appointment

Extra doses (immunocompromised, transplant recipients, dialysis patients and those vaccinated with Johnson & Johnson vaccine) will be given (unless contraindicated by age/health status) with Moderna Spikevax vaccine in the standard dose.

Booster doses (persons aged 12 years or older who have already received a full two-dose vaccination schedule) will be given, unless medically contraindicated, with Moderna Spikevax vaccine at half dose for those aged 30 years and over or Pfizer's Comirnaty vaccine for those aged 12 - 29 years.

People who live in Luxembourg and who received their initial vaccination abroad will be able to go without an appointment to one of the 3 vaccination centres LuxExpo, Esch-Belval or Ettelbruck for their booster vaccination.


Obtaining a certificate of contraindication to vaccination for health reasons

Any person (resident or frontier worker) who for health reasons cannot be vaccinated can ask their doctor to obtain a certificate of contraindication to vaccination against COVID-19. If the request is granted, the certificate and a set of free PCR test vouchers are then sent to the patient.

The contraindications to COVID-19 vaccination are defined by the Health Directorate.


What vaccines are currently available against COVID-19?

4 coronavirus vaccines have received marketing authorisation from the EMA, the European Medicines Agency, and the green light from the European Commission for their use. This process is very important as it ensures the safety and quality of the vaccines as well as their effectiveness.

Other COVID-19 vaccines are still in the process of being submitted for approval by the EMA. These include the Curevac vaccine, Novavax and Sputnik V. 

What is the procedure to get a marketing autorisation for a coronavirus vaccine?

COVID-19 vaccines are developed according to the same strict regulatory requirements for pharmaceutical quality, safety and efficacy, as any other drug.

Before being released on the market, the vaccine goes through several stages, from rigorous tests where the quality of the vaccine is controlled to approval by the European Medicines Agency (EMA), through a scientific evaluation by the regulatory authorities (EMA and other regulators in EU/EEA countries) before its effectiveness is tested through research first in the laboratory and then on volunteers. It should be noted that the clinical trial programme must be carried out in accordance with the procedures and protocols established by the regulatory authorities. It must also be approved in each case by a medical ethics commission.

Who is responsible if COVID-19 vaccines have a negative impact on public health?

As with any other vaccine, it is the manufacturer of the vaccine that is, in principle, responsible in the event of any adverse public health effects. However, the adverse effect must be due to a problem with the product itself, its composition or production.

The physician who carries out the vaccination is also civilly liable if he or she makes a mistake in handling or administering the vaccine, and if this mistake is the cause of the side effects.

Finally, when a vaccination is imposed by a legal or regulatory provision or recommended by the State, and that vaccination causes the death of the vaccinated person or results in permanent physical incapacity, the State is liable for the damage, without prejudice to any action that may be taken in accordance with ordinary law, and insofar as the damage is not compensable under the Social Insurance Code.


Will vaccination against COVID-19 be compulsory?

No. As with most vaccines in our country, vaccination against COVID-19 will be carried out on a voluntary basis.

I have already had COVID-19, can I still get vaccinated?

A person who has been in contact with the coronavirus can be vaccinated against it. At present, it is impossible to say that a person who has already been in contact with COVID-19 remains immune to the disease. It is also not possible, in the case of immunisation, to predict the duration of this immunisation. Unfortunately, reinfections have been reported.

Is a screening test necessary before getting vaccinated?

No, it is not necessary to get tested for COVID-19 before vaccination. Even if you are unknowingly infected, the vaccine can be administered safely.

Does the vaccine also protect against mutations of the virus?

Mutations do not necessarily affect the efficacy of the vaccine against the virus.

The scientific community and regulatory authorities are monitoring whether the coronavirus is changing over time and whether vaccines can protect people against infection with new variants. If it turns out that adjustments need to be made, science will provide an answer to this question, as it does for other viruses to which we have adapted.

Do I have to be vaccinated against coronavirus every year?

It is not possible at this stage to answer this question, as we do not have sufficient hindsight to know exactly how long the immunisation obtained with the vaccine lasts, whether it covers the various mutations of the virus or whether these require the composition of the vaccine to be regularly modified, as is the case, for example, with seasonal influenza. 

After vaccination, am I immediately immune?

About 2 weeks after the first dose of vaccine, the initial immune response provides partial protection against an infection. However, it takes 2 weeks after the second dose of vaccine for the immune response to be fully developed and for an optimal protection against an infection.

As with other vaccines, the COVID-19 vaccine does not provide 100% protection even after the second vaccination. It is still possible to become infected. Vaccination will reduce the symptoms of the disease.

It is important to continue to respect the protective measures in order to avoid as many infections as possible.​

Can I stop following the protective measures after I have been vaccinated?

No. Even after you have been vaccinated, you must continue to respect the protective measures until the health crisis is effectively under control, in particular through herd immunity. It cannot be ruled out at present that a vaccinated person may no longer be a carrier of the virus. However, it will take some time before this immunity is achieved. It ensures that a sufficiently large number of people are immunised. 

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